1pup

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(New page: 200px<br /><applet load="1pup" size="450" color="white" frame="true" align="right" spinBox="true" caption="1pup, resolution 1.700&Aring;" /> '''CRYSTAL STRUCTURE O...)
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Revision as of 00:54, 25 November 2007

Image:1pup.gif

1pup, resolution 1.700Å

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CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION

Overview

The crystal structure of a PNA duplex reveals both a right- and a, left-handed helix in the unit cell. The helices are wide (28A), large, pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide, partners also has a unique structure by itself.

About this Structure

1PUP is a Protein complex structure of sequences from [1] with NH2 as ligand. Full crystallographic information is available from OCA.

Reference

Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585

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