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	[[User:Tilman Schirmer/Sandbox 110|Repetitive torsion angles]]		[[User:Tilman Schirmer/Sandbox 110|Repetitive torsion angles]]
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	[[User:Tilman Schirmer/Sandbox 111|α-Helix]]		[[User:Tilman Schirmer/Sandbox 111|α-Helix]]
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	[[User:Tilman Schirmer/Sandbox 112|parallel β-sheet]]		[[User:Tilman Schirmer/Sandbox 112|parallel β-sheet]]
-	[[User:Tilman Schirmer/Sandbox 113|antiparallel β-sheet]]
-	α-Helix	+	[[User:Tilman Schirmer/Sandbox 113|antiparallel β-sheet]]
-	parallel β-sheet
-	antiparallel β-sheet	+	----
		+	----

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Revision as of 08:17, 10 November 2009

Contents 1 Secondary structure of proteins 1.1 Repetitive torsion angles 1.2 α-Helix 1.3 parallel β-sheet 1.4 antiparallel β-sheet 2 Anatomy of a protein 3 Notes

Secondary structure of proteins

outline:

Repetitive torsion angles

α-Helix

parallel β-sheet

antiparallel β-sheet

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Repetitive torsion angles

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

A polypeptide chain with a repetition of identical phi-psi torsion angles yields a helical structure.

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phi-psi = (180^o, 180^o), fully extended chain: ,

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phi-psi = (-140^o, 130^o), extended chain: , ; this is the β-strand conformation found in beta-sheets

Note:

polypeptide forms a with side-chains protruding towards alternating (up, down) directions

the polypeptide main-chain is as can been seen when looking along the chain

the point towards alternate directions

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phi-psi = (70^o, 180^o): , ; note that there are clashes (where?)

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phi-psi = (-60^o, -40^o), α-helix: ,

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phi-psi = (-50^o, -26^o), 3₁₀ helix: ,

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α-Helix

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

An α-Helix is stabilized by main-chain between O_i and N_i+4. With .

parallel β-sheet

spinqualitylabelsall models PDB ID 1tmy.pdb Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

With .

antiparallel β-sheet

spinqualitylabelsall models PDB ID 1ema.pdb Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

With .

Anatomy of a protein

spinqualitylabelsall models 1tmy Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Response regulator receiver (Rec) domain. See also 1tmy.

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The rest are the irregular .

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Notes

see also http://proteopedia.org/wiki/index.php/User:James_D_Watson/Structural_Templates