3ivc
From Proteopedia
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Revision as of 18:05, 11 November 2009
Crystal structure of pantothenate synthetase in complex with 2-(2-((benzofuran-2-ylmethoxy)carbonyl)-5-methoxy-1H-indol-1-yl)acetic acid
About this Structure
3IVC is a 2 chains structure of sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821
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Categories: Mycobacterium tuberculosis | Pantoate--beta-alanine ligase | Abell, C. | Blundell, T L. | Ciulli, A. | Hung, A W. | Silvestre, H L. | Wen, S. | Atp-binding | Cytoplasm | Fragment-based lead discovery | Ligase | Magnesium | Metal-binding | Nucleotide-binding | Pantothenate biosynthesis | Pantothenate synthetase