2vx1

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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:18851911</ref><ref group="xtra">PMID:18434142</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Unphosphorylated]]
[[Category: Unphosphorylated]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:14:52 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:15:42 2009''

Revision as of 18:15, 11 November 2009

Image:2vx1.png

Template:STRUCTURE 2vx1

EPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18851911

About this Structure

2VX1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bardelle C, Coleman T, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5717-21. Epub 2008 Sep 27. PMID:18851911 doi:10.1016/j.bmcl.2008.09.087
  • Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015

Page seeded by OCA on Wed Nov 11 20:15:42 2009

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