3hpt

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3hpt.jpg|left|200px]]
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The entry 3hpt is ON HOLD until sometime in the future
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{{STRUCTURE_3hpt| PDB=3hpt | SCENE= }}
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Authors: Klei, H.E., Ghosh, K., Rushith, A., Kish, K.
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===Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine===
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Description: CRYSTAL STRUCTURE OF HUMAN FXA IN COMPLEX WITH (S)-2-CYANO-1-(2-METHYLBENZOFURAN-5-YL)-3-(2-OXO-1-(2-OXO-2-(PYRROLIDIN-1-YL)ETHYL)AZEPAN-3-YL)GUANIDINE
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 08:56:21 2009''
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{{ABSTRACT_PUBMED_19541481}}
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==About this Structure==
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3HPT is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HPT OCA].
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==Reference==
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<ref group="xtra">PMID:19541481</ref><references group="xtra"/>
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[[Category: Coagulation factor Xa]]
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[[Category: Homo sapiens]]
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[[Category: Ghosh, K.]]
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[[Category: Kish, K.]]
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[[Category: Klei, H E.]]
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[[Category: Rushith, A.]]
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[[Category: Blood clotting]]
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[[Category: Blood coagulation]]
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[[Category: Blood coagulation factor]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disulfide bond]]
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[[Category: Egf-like domain]]
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[[Category: Epidermal growth factor like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Hydroxylation]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 19:36:45 2009''

Revision as of 17:36, 18 November 2009

Image:3hpt.jpg

Template:STRUCTURE 3hpt

Crystal structure of human FxA in complex with (S)-2-cyano-1-(2-methylbenzofuran-5-yl)-3-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)guanidine

Template:ABSTRACT PUBMED 19541481

About this Structure

3HPT is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Shi Y, Zhang J, Shi M, O'Connor SP, Bisaha SN, Li C, Sitkoff D, Pudzianowski AT, Chong S, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4034-41. Epub 2009 Jun 13. PMID:19541481 doi:10.1016/j.bmcl.2009.06.014

Page seeded by OCA on Wed Nov 18 19:36:45 2009

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