3i9g

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===Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate===
===Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate===
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{{ABSTRACT_PUBMED_19815502}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:19509417</ref><references group="xtra"/>
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<ref group="xtra">PMID:19815502</ref><ref group="xtra">PMID:19509417</ref><references group="xtra"/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Huxford, T.]]
[[Category: Huxford, T.]]
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[[Category: Sphingosine-1-phosphate]]
[[Category: Sphingosine-1-phosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 09:49:31 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 25 10:04:40 2009''

Revision as of 08:04, 25 November 2009

Image:3i9g.png

Template:STRUCTURE 3i9g

Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate

Template:ABSTRACT PUBMED 19815502

About this Structure

3I9G is a 2 chains structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Wojciak JM, Zhu N, Schuerenberg KT, Moreno K, Shestowsky WS, Hiraiwa M, Sabbadini R, Huxford T. The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17717-22. Epub 2009 Oct 7. PMID:19815502
  • O'Brien N, Jones ST, Williams DG, Cunningham HB, Moreno K, Visentin B, Gentile A, Vekich J, Shestowsky W, Hiraiwa M, Matteo R, Cavalli A, Grotjahn D, Grant M, Hansen G, Campbell MA, Sabbadini R. Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies. J Lipid Res. 2009 Nov;50(11):2245-57. Epub 2009 Jun 9. PMID:19509417 doi:10.1194/jlr.M900048-JLR200

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