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2c26
From Proteopedia
(New page: 200px<br /> <applet load="2c26" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c26, resolution 2.10Å" /> '''STRUCTURAL BASIS FO...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2C26 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]] with CA and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C26 OCA]]. | + | 2C26 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]] with CA and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C26 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: pkd domain]] | [[Category: pkd domain]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:48:02 2007'' |
Revision as of 06:43, 30 October 2007
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STRUCTURAL BASIS FOR THE PROMISCUOUS SPECIFICITY OF THE CARBOHYDRATE-BINDING MODULES FROM THE BETA-SANDWICH SUPER FAMILY
Overview
Enzyme systems that attack the plant cell wall contain noncatalytic, carbohydrate-binding modules (CBMs) that mediate attachment to this, composite structure and play a pivotal role in maximizing the hydrolytic, process. Although xyloglucan, which includes a backbone of beta-1,4-glucan, decorated primarily with xylose residues, is a key component of the plant, cell wall, CBMs that bind to this polymer have not been identified. Here, we showed that the C-terminal domain of the modular Clostridium, thermocellum enzyme CtCel9D-Cel44A (formerly known as CelJ) comprises a, novel CBM (designated CBM44) that binds with equal affinity to cellulose, and xyloglucan. We also showed that accommodation of xyloglucan side, chains is a general feature of CBMs that bind to single cellulose chains., The ... [(full description)]
About this Structure
2C26 is a [Single protein] structure of sequence from [Clostridium thermocellum] with CA and EDO as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Xyloglucan is recognized by carbohydrate-binding modules that interact with beta-glucan chains., Najmudin S, Guerreiro CI, Carvalho AL, Prates JA, Correia MA, Alves VD, Ferreira LM, Romao MJ, Gilbert HJ, Bolam DN, Fontes CM, J Biol Chem. 2006 Mar 31;281(13):8815-28. Epub 2005 Nov 28. PMID:16314409
Page seeded by OCA on Tue Oct 30 08:48:02 2007
Categories: Clostridium thermocellum | Single protein | Alves, V.D. | Bolam, D.N. | Carvalho, A.L. | Correia, M.A.S. | Ferreira, L.M.A. | Fontes, C.M.G.A. | Gilbert, H.J. | Guerreiro, C.I.P.D. | Najmudin, S. | Prates, J.A.M. | Romao, M.J. | CA | EDO | Beta-sandwich proteins | Carbohydrate binding module | Cbm44 | Cellulase ctcel9d-cel44a | Cellulosome | Hydrolase | Pkd domain
