1a65
From Proteopedia
(New page: 200px<br /> <applet load="1a65" size="450" color="white" frame="true" align="right" spinBox="true" caption="1a65, resolution 2.23Å" /> '''TYPE-2 CU-DEPLETED ...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Coprinus_cinereus Coprinus cinereus]] with NAG, GLC, CU and O as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A65 OCA]]. | + | 1A65 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Coprinus_cinereus Coprinus cinereus]] with NAG, GLC, CU and O as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.2 1.10.3.2]]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1A65 OCA]]. |
==Reference== | ==Reference== | ||
| Line 27: | Line 27: | ||
[[Category: type-2 copper depleted]] | [[Category: type-2 copper depleted]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:48:21 2007'' |
Revision as of 06:43, 30 October 2007
|
TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS
Overview
Laccase catalyses the oxidation of a variety of organic substrates coupled, to the reduction of oxygen to water. It is widely believed to be the, simplest representative of the ubiquitous blue multi-copper oxidase, family. Laccase is implicated in a wide spectrum of biological activities, and, in particular, plays a key role in morphogenesis, development and, lignin metabolism in fungi and plants. The structure of laccase from the, fungus Coprinus cinereus has been determined by X-ray crystallography at a, resolution of 2.2 A. Laccase is a monomer composed of three, cupredoxin-like beta-sandwich domains, similar to that found in ascorbate, oxidase. In contrast to ascorbate oxidase, however, the mononuclear type-1, Cu site lacks the axial methionine ligand and so exhibits trigonal planar, ... [(full description)]
About this Structure
1A65 is a [Single protein] structure of sequence from [Coprinus cinereus] with NAG, GLC, CU and O as [ligands]. Active as [Oxidoreductase], with EC number [1.10.3.2]. Structure known Active Sites: T1 and T3. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:9546223
Page seeded by OCA on Tue Oct 30 08:48:21 2007
Categories: Coprinus cinereus | Single protein | Brzozowski, W. | Ducros, V. | CU | GLC | NAG | O | Blue multi-copper oxidase | Glycoprotein | Laccase | Oxidoreductase | Signal | Type-2 copper depleted
