3igv

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3igv.jpg|left|200px]]
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The entry 3igv is ON HOLD until Paper Publication
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{{STRUCTURE_3igv| PDB=3igv | SCENE= }}
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Authors: Zhao, Q., Showalter, R.E., Han, Q., Kissinger, C.R.
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===Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor===
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Description: Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:25:34 2009''
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{{ABSTRACT_PUBMED_19796938}}
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==About this Structure==
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3IGV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGV OCA].
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==Reference==
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<ref group="xtra">PMID:19796938</ref><references group="xtra"/>
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Viruses]]
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[[Category: Han, Q.]]
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[[Category: Kissinger, C R.]]
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[[Category: Showalter, R E.]]
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[[Category: Zhao, Q.]]
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[[Category: Antiviral]]
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[[Category: Atp-binding]]
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[[Category: Disulfide bond]]
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[[Category: Host-virus interaction]]
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[[Category: Hydrolase]]
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[[Category: Metal binding]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Nucleus]]
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[[Category: Protein-ligand complex]]
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[[Category: Rna replication]]
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[[Category: Rna-binding]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transferase]]
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[[Category: Viral nucleoprotein]]
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[[Category: Virion]]
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[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:00:07 2009''

Revision as of 13:00, 9 December 2009

Image:3igv.jpg

Template:STRUCTURE 3igv

Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor

Template:ABSTRACT PUBMED 19796938

About this Structure

3IGV is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  • Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051

Page seeded by OCA on Wed Dec 9 15:00:07 2009

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