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3jqd
From Proteopedia
(Difference between revisions)
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| + | {{STRUCTURE_3jqd| PDB=3jqd | SCENE= }} | ||
| - | + | ===Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX7)=== | |
| - | Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX7) | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19916554}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19916554 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19916554}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 3JQD is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQD OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19916554</ref><references group="xtra"/> | ||
| + | [[Category: Pteridine reductase]] | ||
| + | [[Category: Trypanosoma brucei]] | ||
| + | [[Category: Hunter, W N.]] | ||
| + | [[Category: Tulloch, L B.]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Pteridine reductase]] | ||
| + | [[Category: Ptr1]] | ||
| + | [[Category: Short chain dehydrogenase]] | ||
| + | [[Category: Trypanosoma brucei]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:03:14 2009'' | ||
Revision as of 13:03, 9 December 2009
Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX7)
Template:ABSTRACT PUBMED 19916554
About this Structure
3JQD is a 4 chains structure of sequences from Trypanosoma brucei. Full crystallographic information is available from OCA.
Reference
- Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x
Page seeded by OCA on Wed Dec 9 15:03:14 2009
