3jqc

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3jqc.jpg|left|200px]]
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The entry 3jqc is ON HOLD until Paper Publication
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{{STRUCTURE_3jqc| PDB=3jqc | SCENE= }}
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Authors: Tulloch, L.B., Hunter, W.N.
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===Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2)===
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Description: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:30:01 2009''
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{{ABSTRACT_PUBMED_19916554}}
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==About this Structure==
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3JQC is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQC OCA].
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==Reference==
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<ref group="xtra">PMID:19916554</ref><references group="xtra"/>
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[[Category: Pteridine reductase]]
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[[Category: Trypanosoma brucei]]
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[[Category: Hunter, W N.]]
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[[Category: Tulloch, L B.]]
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[[Category: Inhibitor]]
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[[Category: Oxidoreductase]]
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[[Category: Pteridine reductase]]
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[[Category: Ptr1]]
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[[Category: Short chain dehydrogenase]]
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[[Category: Trypanosoma brucei]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:04:03 2009''

Revision as of 13:04, 9 December 2009

Image:3jqc.jpg

Template:STRUCTURE 3jqc

Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2)

Template:ABSTRACT PUBMED 19916554

About this Structure

3JQC is a 4 chains structure of sequences from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  • Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x

Page seeded by OCA on Wed Dec 9 15:04:03 2009

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