3gyn
From Proteopedia
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| + | {{STRUCTURE_3gyn| PDB=3gyn | SCENE= }} | ||
| - | + | ===Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor=== | |
| - | Description: Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19796938}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19796938 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19796938}} | ||
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| + | ==About this Structure== | ||
| + | 3GYN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYN OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19796938</ref><references group="xtra"/> | ||
| + | [[Category: RNA-directed RNA polymerase]] | ||
| + | [[Category: Viruses]] | ||
| + | [[Category: Han, Q.]] | ||
| + | [[Category: Kissinger, C R.]] | ||
| + | [[Category: Showalter, R E.]] | ||
| + | [[Category: Zhao, Q.]] | ||
| + | [[Category: Acetylation]] | ||
| + | [[Category: Apoptosis]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Capsid protein]] | ||
| + | [[Category: Cell membrane]] | ||
| + | [[Category: Cytoplasm]] | ||
| + | [[Category: Disulfide bond]] | ||
| + | [[Category: Endoplasmic reticulum]] | ||
| + | [[Category: Envelope protein]] | ||
| + | [[Category: Fusion protein]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Helicase]] | ||
| + | [[Category: Host-virus interaction]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Interferon antiviral system evasion]] | ||
| + | [[Category: Lipid droplet]] | ||
| + | [[Category: Lipoprotein]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Mitochondrion]] | ||
| + | [[Category: Multifunctional enzyme]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleotidyltransferase]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Oncogene]] | ||
| + | [[Category: Palmitate]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Protein-ligand complex]] | ||
| + | [[Category: Ribonucleoprotein]] | ||
| + | [[Category: Rna replication]] | ||
| + | [[Category: Rna-binding]] | ||
| + | [[Category: Rna-directed rna polymerase]] | ||
| + | [[Category: Secreted]] | ||
| + | [[Category: Serine protease]] | ||
| + | [[Category: Sh3-binding]] | ||
| + | [[Category: Thiol protease]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transcription regulation]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transmembrane]] | ||
| + | [[Category: Ubl conjugation]] | ||
| + | [[Category: Viral nucleoprotein]] | ||
| + | [[Category: Virion]] | ||
| + | [[Category: Zinc]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:05:50 2009'' | ||
Revision as of 13:05, 9 December 2009
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor
Template:ABSTRACT PUBMED 19796938
About this Structure
3GYN is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.
Reference
- Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051
Page seeded by OCA on Wed Dec 9 15:05:50 2009
Categories: RNA-directed RNA polymerase | Viruses | Han, Q. | Kissinger, C R. | Showalter, R E. | Zhao, Q. | Acetylation | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Cytoplasm | Disulfide bond | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Helicase | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Protein-ligand complex | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transmembrane | Ubl conjugation | Viral nucleoprotein | Virion | Zinc
