3gc5

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3gc5.jpg|left|200px]]
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The entry 3gc5 is ON HOLD until Paper Publication
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{{STRUCTURE_3gc5| PDB=3gc5 | SCENE= }}
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Authors: Ritschel, T., Heine, A., Klebe, G.
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===tRNA-guanine transglycosylase in complex with 6-amino-4-(2-aminoethyl)-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one===
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Description: tRNA-guanine transglycosylase in complex with 6-amino-4-(2-aminoethyl)-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 15:18:11 2009''
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{{ABSTRACT_PUBMED_19894214}}
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==About this Structure==
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3GC5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GC5 OCA].
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==Reference==
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<ref group="xtra">PMID:19894214</ref><references group="xtra"/>
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[[Category: Queuine tRNA-ribosyltransferase]]
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[[Category: Zymomonas mobilis]]
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[[Category: Heine, A.]]
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[[Category: Klebe, G.]]
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[[Category: Ritschel, T.]]
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[[Category: Drug design]]
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[[Category: Glycosyltransferase]]
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[[Category: Metal-binding]]
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[[Category: Queuosine biosynthesis]]
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[[Category: Tim barrel]]
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[[Category: Transferase]]
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[[Category: Trna modification]]
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[[Category: Trna processing]]
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[[Category: Zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 13:33:48 2009''

Revision as of 11:33, 16 December 2009

Template:STRUCTURE 3gc5

tRNA-guanine transglycosylase in complex with 6-amino-4-(2-aminoethyl)-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 19894214

About this Structure

3GC5 is a 1 chain structure of sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

  • Ritschel T, Kohler PC, Neudert G, Heine A, Diederich F, Klebe G. How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase. ChemMedChem. 2009 Dec;4(12):2012-23. PMID:19894214 doi:10.1002/cmdc.200900343

Page seeded by OCA on Wed Dec 16 13:33:48 2009

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