3fli
From Proteopedia
(Difference between revisions)
Line 12: | Line 12: | ||
===Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)=== | ===Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)=== | ||
+ | |||
+ | <!-- | ||
+ | The line below this paragraph, {{ABSTRACT_PUBMED_19159286}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 19159286 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_19159286}} | ||
==About this Structure== | ==About this Structure== | ||
Line 41: | Line 47: | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:31:14 2009'' |
Revision as of 05:31, 24 December 2009
Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)
Template:ABSTRACT PUBMED 19159286
About this Structure
3FLI is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Flatt B, Martin R, Wang TL, Mahaney P, Murphy B, Gu XH, Foster P, Li J, Pircher P, Petrowski M, Schulman I, Westin S, Wrobel J, Yan G, Bischoff E, Daige C, Mohan R. Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR). J Med Chem. 2009 Feb 26;52(4):904-7. PMID:19159286 doi:10.1021/jm8014124
Page seeded by OCA on Thu Dec 24 07:31:14 2009
Categories: Homo sapiens | Foster, P G. | Stout, T J. | Activator | Alpha-helical sandwich | Alternative splicing | Bar | Bile acid receptor | Dna-binding | Fxr | Ligand-binding domain | Metal-binding | Nr1h4 | Nuclear receptor | Nucleus | Receptor | Repressor | Transcription | Transcription regulation | Transcriptional regulator | Zinc | Zinc-finger