3jsw
From Proteopedia
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===Human PDE9 in complex with selective inhibitor=== | ===Human PDE9 in complex with selective inhibitor=== | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_19919087}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19919087 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19919087}} | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:32:29 2009'' |
Revision as of 05:32, 24 December 2009
Human PDE9 in complex with selective inhibitor
Template:ABSTRACT PUBMED 19919087
About this Structure
3JSW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334
Page seeded by OCA on Thu Dec 24 07:32:29 2009
