3jy9
From Proteopedia
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3jy9. | + | [[Image:3jy9.png|left|200px]] |
<!-- | <!-- | ||
| Line 12: | Line 12: | ||
===Janus Kinase 2 Inhibitors=== | ===Janus Kinase 2 Inhibitors=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20014869}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20014869 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20014869}} | ||
==Disease== | ==Disease== | ||
| Line 18: | Line 24: | ||
==About this Structure== | ==About this Structure== | ||
3JY9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JY9 OCA]. | 3JY9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JY9 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20014869</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| Line 39: | Line 48: | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 14:05:18 2009'' |
Revision as of 12:05, 30 December 2009
Contents |
Janus Kinase 2 Inhibitors
Template:ABSTRACT PUBMED 20014869
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
3JY9 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wang T, Duffy JP, Wang J, Halas S, Salituro FG, Pierce AC, Zuccola HJ, Black JR, Hogan JK, Jepson S, Shlyakter D, Mahajan S, Gu Y, Hoock T, Wood M, Furey BF, Frantz JD, Dauffenbach LM, Germann UA, Fan B, Namchuk M, Bennani YL, Ledeboer MW. Janus kinase 2 inhibitors. Synthesis and characterization of a novel polycyclic azaindole. J Med Chem. 2009 Dec 24;52(24):7938-41. PMID:20014869 doi:10.1021/jm901383u
Page seeded by OCA on Wed Dec 30 14:05:18 2009
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Ledeboer, M W. | Pierce, A C. | Zuccola, H J. | Atp-binding | Chromosomal rearrangement | Disease mutation | Inhibitor | Jak2 | Janus kinase | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
