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3kwh

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(New page: '''Unreleased structure''' The entry 3kwh is ON HOLD Authors: Hennig, M., Stihle, M., Thoma, R. Description: Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-Butyl-9,10-dimethoxy-...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3kwh.jpg|left|200px]]
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The entry 3kwh is ON HOLD
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{{STRUCTURE_3kwh| PDB=3kwh | SCENE= }}
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Authors: Hennig, M., Stihle, M., Thoma, R.
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===Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-Butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine===
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Description: Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-Butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:45:28 2009''
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{{ABSTRACT_PUBMED_20031405}}
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==About this Structure==
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3KWH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KWH OCA].
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==Reference==
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<ref group="xtra">PMID:20031405</ref><references group="xtra"/>
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[[Category: Dipeptidyl-peptidase IV]]
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[[Category: Homo sapiens]]
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[[Category: Hennig, M.]]
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[[Category: Stihle, M.]]
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[[Category: Thoma, R.]]
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[[Category: Aminopeptidase]]
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[[Category: Cell membrane]]
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[[Category: Diabetes type ii]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Signal-anchor]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:50:33 2010''

Revision as of 11:50, 13 January 2010

Template:STRUCTURE 3kwh

Structure of human DPP-IV with HTS hit (2S,3S,11bS)-3-Butyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine

Template:ABSTRACT PUBMED 20031405

About this Structure

3KWH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mattei P, Boehringer M, Di Giorgio P, Fischer H, Hennig M, Huwyler J, Kocer B, Kuhn B, Loeffler BM, Macdonald A, Narquizian R, Rauber E, Sebokova E, Sprecher U. Discovery of carmegliptin: a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1109-13. Epub 2009 Dec 6. PMID:20031405 doi:10.1016/j.bmcl.2009.12.024

Page seeded by OCA on Wed Jan 13 13:50:33 2010

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