3fra

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3fra.jpg|left|200px]]
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The entry 3fra is ON HOLD until Jan 08 2011
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{{STRUCTURE_3fra| PDB=3fra | SCENE= }}
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Authors: Oefner, C., Dale-Glenn, E.
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===Staphylococcus aureus F98Y DHFR complexed with iclaprim===
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Description: Staphylococcus aureus F98Y DHFR complexed with iclaprim
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:23:40 2009''
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{{ABSTRACT_PUBMED_19211577}}
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==About this Structure==
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3FRA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRA OCA].
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==Reference==
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<ref group="xtra">PMID:19211577</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus]]
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[[Category: Dale-Glenn, E.]]
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[[Category: Oefner, C.]]
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[[Category: Dhfr]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:00:06 2010''

Revision as of 12:00, 13 January 2010

Template:STRUCTURE 3fra

Staphylococcus aureus F98Y DHFR complexed with iclaprim

Template:ABSTRACT PUBMED 19211577

About this Structure

3FRA is a 1 chain structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024

Page seeded by OCA on Wed Jan 13 14:00:06 2010

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