3frd

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3frd.jpg|left|200px]]
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The entry 3frd is ON HOLD until Jan 08 2011
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{{STRUCTURE_3frd| PDB=3frd | SCENE= }}
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Authors: Oefner, C., Dale-Glenn, E.
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===S. aureus DHFR complexed with NADPH and folate===
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Description: S. aureus DHFR complexed with NADPH and folate
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:23:45 2009''
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{{ABSTRACT_PUBMED_19211577}}
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==About this Structure==
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3FRD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FRD OCA].
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==Reference==
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<ref group="xtra">PMID:19211577</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus]]
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[[Category: Dale-Glenn, E.]]
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[[Category: Oefner, C.]]
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[[Category: Nadp]]
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[[Category: One-carbon metabolism]]
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[[Category: Oxidoreductase]]
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[[Category: S aureus dhfr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 14:13:04 2010''

Revision as of 12:13, 13 January 2010

Template:STRUCTURE 3frd

S. aureus DHFR complexed with NADPH and folate

Template:ABSTRACT PUBMED 19211577

About this Structure

3FRD is a 1 chain structure of sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

Reference

  • Oefner C, Bandera M, Haldimann A, Laue H, Schulz H, Mukhija S, Parisi S, Weiss L, Lociuro S, Dale GE. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity. J Antimicrob Chemother. 2009 Apr;63(4):687-98. Epub 2009 Feb 11. PMID:19211577 doi:10.1093/jac/dkp024

Page seeded by OCA on Wed Jan 13 14:13:04 2010

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