452d

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==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=452D OCA].
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452D is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=452D OCA].
==Reference==
==Reference==
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Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
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<ref group="xtra">PMID:10052960</ref><references group="xtra"/>
[[Category: Cardin, C J.]]
[[Category: Cardin, C J.]]
[[Category: Thorpe, J H.]]
[[Category: Thorpe, J H.]]
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[[Category: Intercalation]]
[[Category: Intercalation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:21:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 08:48:21 2010''

Revision as of 06:48, 18 January 2010

Template:STRUCTURE 452d

ACRIDINE BINDING TO DNA

About this Structure

452D is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ. Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution. J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960 doi:10.1021/jm980479u

Page seeded by OCA on Mon Jan 18 08:48:21 2010

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