3gen

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3gen.jpg|left|200px]]
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The entry 3gen is ON HOLD until Paper Publication
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{{STRUCTURE_3gen| PDB=3gen | SCENE= }}
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Authors: Marcotte, D.J., Liu, Y.T., Arduini, R.M., Hession, C.A., Miatkowski, K., Wildes, C.P., Cullen, P.F., Hopkins, B., Mertsching, E., Jenkins, T.J., Romanowski, M.J., Baker, D.P., Silvian, L.F.
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===The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound===
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Description: The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:14:52 2009''
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{{ABSTRACT_PUBMED_20052711}}
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==About this Structure==
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3GEN is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEN OCA].
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==Reference==
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<ref group="xtra">PMID:20052711</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Arduini, R M.]]
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[[Category: Baker, D P.]]
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[[Category: Cullen, P F.]]
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[[Category: Hession, C A.]]
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[[Category: Hopkins, B.]]
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[[Category: Jenkins, T J.]]
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[[Category: Liu, Y T.]]
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[[Category: Marcotte, D J.]]
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[[Category: Mertsching, E.]]
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[[Category: Miatkowski, K.]]
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[[Category: Romanowski, M J.]]
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[[Category: Silvian, L F.]]
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[[Category: Wildes, C P.]]
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[[Category: Acetylation]]
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[[Category: Atp-binding]]
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[[Category: Bruton's tyrosine kinase]]
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[[Category: Complex]]
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[[Category: Cytoplasm]]
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[[Category: Disease mutation]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Sh2 domain]]
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[[Category: Sh3 domain]]
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[[Category: Tec-family]]
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[[Category: Transferase]]
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[[Category: Tyrosine-protein kinase]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 15:44:40 2010''

Revision as of 13:44, 20 January 2010

Image:3gen.jpg

Template:STRUCTURE 3gen

The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound

Template:ABSTRACT PUBMED 20052711

About this Structure

3GEN is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for tec family kinases. Protein Sci. 2010 Jan 5. PMID:20052711 doi:10.1002/pro.321

Page seeded by OCA on Wed Jan 20 15:44:40 2010

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OCA

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