3kmy
From Proteopedia
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| + | {{STRUCTURE_3kmy| PDB=3kmy | SCENE= }} | ||
| - | + | ===Structure of BACE bound to SCH12472=== | |
| - | Description: Structure of BACE bound to SCH12472 | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20043700}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20043700 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20043700}} | ||
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| + | ==About this Structure== | ||
| + | 3KMY is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMY OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20043700</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Strickland, C.]] | ||
| + | [[Category: Wang, Y.]] | ||
| + | [[Category: Alternative splicing]] | ||
| + | [[Category: Alzheimers']] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Bace1]] | ||
| + | [[Category: Disulfide bond]] | ||
| + | [[Category: Endoplasmic reticulum]] | ||
| + | [[Category: Endosome]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Golgi apparatus]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Transmembrane]] | ||
| + | [[Category: Zymogen]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 16:01:13 2010'' | ||
Revision as of 14:01, 20 January 2010
Structure of BACE bound to SCH12472
Template:ABSTRACT PUBMED 20043700
About this Structure
3KMY is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wang YS, Strickland C, Voigt JH, Kennedy ME, Beyer BM, Senior MM, Smith EM, Nechuta TL, Madison VS, Czarniecki M, McKittrick BA, Stamford AW, Parker EM, Hunter JC, Greenlee WJ, Wyss DF. Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J Med Chem. 2009 Dec 31. PMID:20043700 doi:10.1021/jm901472u
Page seeded by OCA on Wed Jan 20 16:01:13 2010
