3jqe
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 3JQE is a 4 chains structure | + | 3JQE is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3bmk 3bmk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQE OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 16:40:53 2010'' |
Revision as of 14:40, 20 January 2010
Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-(4-methoxyphenyl)-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX8)
Template:ABSTRACT PUBMED 19916554
About this Structure
3JQE is a 4 chains structure with sequences from Trypanosoma brucei. This structure supersedes the now removed PDB entry 3bmk. Full crystallographic information is available from OCA.
Reference
- Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x
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