1a36

From Proteopedia

(Difference between revisions)

Revision as of 06:10, 21 January 2010

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

Image:1a36.png

1a36, resolution 2.80Å ()

Activity:

DNA topoisomerase, with EC number 5.99.1.2

Structural annotation:
Resources:	CATH : 1A36A03, 1A36A02, 1A36A01, 1A36A04 InterPro : Ipr011010, Ipr009054, Ipr013500, Ipr013499, Ipr001631, Ipr013030, Ipr008336, Ipr014727, Ipr014711 Pfam : PF02919, PF01028 SCOP : d1a36a2, d1a36a1, d1a36a3 UniProt : P11387

Functional annotation:
Cellular component:	nucleolus perikaryon chromosome nucleoplasm cytoplasm nucleus
Biological process:	DNA unwinding during replication response to drug embryonic cleavage phosphorylation DNA topological change programmed cell death DNA replication
Molecular function:	DNA topoisomerase activity DNA topoisomerase (ATP-hydrolyzing) activity DNA binding chromatin binding protein binding isomerase activity DNA topoisomerase type I activity

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

TOPOISOMERASE I/DNA COMPLEX

Template:ABSTRACT PUBMED 9488652

About this Structure

1A36 is a 3 chains structure with sequences from Homo sapiens. The January 2006 RCSB PDB Molecule of the Month feature on Topoisomerases by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_1. Full crystallographic information is available from OCA.

Reference

Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ. A model for the mechanism of human topoisomerase I. Science. 1998 Mar 6;279(5356):1534-41. PMID:9488652

Page seeded by OCA on Thu Jan 21 08:10:13 2010

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1a36"

@@ Line 20: / Line 20: @@
 ==About this Structure==
-A36 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The January 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Topoisomerases''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_1 10.2210/rcsb_pdb/mom_2006_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A36 OCA].
+A36 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The January 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Topoisomerases''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_1 10.2210/rcsb_pdb/mom_2006_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A36 OCA].
 ==Reference==
@@ Line 26: / Line 26: @@
 [[Category: DNA topoisomerase]]
 [[Category: Homo sapiens]]
+[[Category: RCSB PDB Molecule of the Month]]
 [[Category: Topoisomerases]]
 [[Category: Champoux, J J.]]
@@ Line 35: / Line 36: @@
 [[Category: Topoisomerase i]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:55:29 2009''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 08:10:13 2010''

1a36

From Proteopedia

Revision as of 06:10, 21 January 2010

TOPOISOMERASE I/DNA COMPLEX

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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