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1fkn
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 1FKN is a 4 chains structure | + | 1FKN is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. The July 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''beta-Secretase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_7 10.2210/rcsb_pdb/mom_2009_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FKN OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Beta-Secretase]] | [[Category: Beta-Secretase]] | ||
[[Category: Ghosh, A.]] | [[Category: Ghosh, A.]] | ||
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[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:57:25 2010'' |
Revision as of 07:57, 21 January 2010
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| 1fkn, resolution 1.90Å () | |||||||||
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| Non-Standard Residues: | |||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Structure of Beta-Secretase Complexed with Inhibitor
Template:ABSTRACT PUBMED 11021803
About this Structure
1FKN is a 4 chains structure with sequences from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.
Reference
- Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803
Page seeded by OCA on Thu Jan 21 09:57:25 2010
Categories: Amyloid-beta Precursor Protein | Homo sapiens | Memapsin 2 | RCSB PDB Molecule of the Month | Beta-Secretase | Ghosh, A. | Hong, L. | Koelsch, G. | Lin, X. | Tang, J. | Terzyan, S. | Wu, S. | Zhang, X C. | Alzheimer's disease | Aspartic protease | Base | Beta-secretase | Hydrolase/hydrolase inhibitor complex
