1t25

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==About this Structure==
==About this Structure==
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1T25 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. The June 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T25 OCA].
+
1T25 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. The June 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T25 OCA].
==Reference==
==Reference==
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[[Category: Lactate Dehydrogenase]]
[[Category: Lactate Dehydrogenase]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
 +
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Barros, D.]]
[[Category: Barros, D.]]
[[Category: Brady, R L.]]
[[Category: Brady, R L.]]
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[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Oct 1 13:39:15 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 10:11:24 2010''

Revision as of 08:11, 21 January 2010

Image:1t25.png

Template:STRUCTURE 1t25

Plasmodium falciparum lactate dehydrogenase complexed with NADH and 3-hydroxyisoxazole-4-carboxylic acid

Template:ABSTRACT PUBMED 15117937

About this Structure

1T25 is a 1 chain structure with sequence from Plasmodium falciparum. The June 2008 RCSB PDB Molecule of the Month feature on Lactate Dehydrogenase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_6. Full crystallographic information is available from OCA.

Reference

  • Cameron A, Read J, Tranter R, Winter VJ, Sessions RB, Brady RL, Vivas L, Easton A, Kendrick H, Croft SL, Barros D, Lavandera JL, Martin JJ, Risco F, Garcia-Ochoa S, Gamo FJ, Sanz L, Leon L, Ruiz JR, Gabarro R, Mallo A, Gomez de las Heras F. Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. J Biol Chem. 2004 Jul 23;279(30):31429-39. Epub 2004 Apr 26. PMID:15117937 doi:10.1074/jbc.M402433200

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