3kmc

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===Crystal structure of catalytic domain of TACE with tartrate-based inhibitor===
===Crystal structure of catalytic domain of TACE with tartrate-based inhibitor===
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The line below this paragraph, {{ABSTRACT_PUBMED_20022498}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20022498 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20022498}}
==About this Structure==
==About this Structure==
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3KMC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMC OCA].
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3KMC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMC OCA].
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==Reference==
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<ref group="xtra">PMID:20022498</ref><references group="xtra"/>
[[Category: ADAM 17 endopeptidase]]
[[Category: ADAM 17 endopeptidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 10:17:49 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:39:04 2010''

Revision as of 17:39, 27 January 2010

Image:3kmc.png

Template:STRUCTURE 3kmc

Crystal structure of catalytic domain of TACE with tartrate-based inhibitor

Template:ABSTRACT PUBMED 20022498

About this Structure

3KMC is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rosner KE, Guo Z, Orth P, Shipps GW Jr, Belanger DB, Chan TY, Curran PJ, Dai C, Deng Y, Girijavallabhan VM, Hong L, Lavey BJ, Lee JF, Li D, Liu Z, Popovici-Muller J, Ting PC, Vaccaro H, Wang L, Wang T, Yu W, Zhou G, Niu X, Sun J, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Arshad Siddiqui M, Strickland CO. The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93. Epub 2009 Dec 5. PMID:20022498 doi:10.1016/j.bmcl.2009.12.004

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