3iw4

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==About this Structure==
==About this Structure==
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3IW4 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].
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3IW4 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].
==Reference==
==Reference==
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[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 11:01:42 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:38:38 2010''

Revision as of 12:38, 28 January 2010

Image:3iw4.png

Template:STRUCTURE 3iw4

Crystal structure of PKC alpha in complex with NVP-AEB071

Template:ABSTRACT PUBMED 19827831

About this Structure

3IW4 is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b

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