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3hxq
From Proteopedia
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| - | [[Image:3hxq. | + | [[Image:3hxq.png|left|200px]] |
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==About this Structure== | ==About this Structure== | ||
| - | 3HXQ is a 2 chains structure | + | 3HXQ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXQ OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Vwf]] | [[Category: Vwf]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:54:28 2010'' |
Revision as of 12:54, 28 January 2010
Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with DNA Aptamer ARC1172, an Inhibitor of VWF-Platelet Binding
About this Structure
3HXQ is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gilbert JC, DeFeo-Fraulini T, Hutabarat RM, Horvath CJ, Merlino PG, Marsh HN, Healy JM, Boufakhreddine S, Holohan TV, Schaub RG. First-in-human evaluation of anti von Willebrand factor therapeutic aptamer ARC1779 in healthy volunteers. Circulation. 2007 Dec 4;116(23):2678-86. Epub 2007 Nov 19. PMID:18025536 doi:10.1161/CIRCULATIONAHA.107.724864
- Diener JL, Daniel Lagasse HA, Duerschmied D, Merhi Y, Tanguay JF, Hutabarat R, Gilbert J, Wagner DD, Schaub R. Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779. J Thromb Haemost. 2009 Jul;7(7):1155-62. Epub 2009 Apr 24. PMID:19422452 doi:10.1111/j.1538-7836.2009.03459.x
Page seeded by OCA on Thu Jan 28 14:54:28 2010
Categories: Homo sapiens | Diener, J L. | Fremont, D H. | Huang, R H. | Sadler, J E. | Schaub, R G. | Aptamer | Arc1772 | Arc1779 | Blood clotting/blood clotting regulator complex | Blood coagulation | Cell adhesion | Cleavage on pair of basic residue | Disease mutation | Disulfide bond | Extracellular matrix | Glycoprotein | Hemostasis | Isopeptide bond | Platelet glycoprotein ib | Polymorphism | Secreted | Ubl conjugation | Von willebrand disease | Vwf
