3inm

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==About this Structure==
==About this Structure==
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3INM is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INM OCA].
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3INM is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3INM OCA].
==Reference==
==Reference==
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[[Category: Tricarboxylic acid cycle]]
[[Category: Tricarboxylic acid cycle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 14:10:57 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:59:35 2010''

Revision as of 12:59, 28 January 2010

Template:STRUCTURE 3inm

Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase R132H mutant in complex with NADPH, ALPHA-KETOGLUTARATE and CALCIUM(2+)

Template:ABSTRACT PUBMED 19935646

About this Structure

3INM is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dang L, White DW, Gross S, Bennett BD, Bittinger MA, Driggers EM, Fantin VR, Jang HG, Jin S, Keenan MC, Marks KM, Prins RM, Ward PS, Yen KE, Liau LM, Rabinowitz JD, Cantley LC, Thompson CB, Vander Heiden MG, Su SM. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009 Dec 10;462(7274):739-44. Epub . PMID:19935646 doi:10.1038/nature08617

Page seeded by OCA on Thu Jan 28 14:59:35 2010

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