2x38

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Revision as of 07:29, 3 February 2010

Image:2x38.jpg

Template:STRUCTURE 2x38

THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH IC87114.

Template:ABSTRACT PUBMED 20081827

About this Structure

2X38 is a 1 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 2wxe. Full crystallographic information is available from OCA.

Reference

  • Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Ruckle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol. 2010 Feb;6(2):117-24. PMID:20081827 doi:10.1038/nchembio.293

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