3ion

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ion.jpg|left|200px]]
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The entry 3ion is ON HOLD until Paper Publication
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{{STRUCTURE_3ion| PDB=3ion | SCENE= }}
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Authors: Olland, A.M.
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===PDK1 in complex with Compound 8h===
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Description: PDK1 in complex with Compound 8h
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:15:31 2010''
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{{ABSTRACT_PUBMED_20074837}}
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==About this Structure==
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3ION is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ION OCA].
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==Reference==
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<ref group="xtra">PMID:20074837</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Olland, A M.]]
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[[Category: Alternative splicing]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Pdk-1]]
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[[Category: Phosphoprotein]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 17:15:25 2010''

Revision as of 15:15, 10 February 2010

Image:3ion.jpg

Template:STRUCTURE 3ion

PDK1 in complex with Compound 8h

Template:ABSTRACT PUBMED 20074837

About this Structure

3ION is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-y lamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur J Med Chem. 2010 Apr;45(4):1379-86. Epub 2009 Dec 28. PMID:20074837 doi:10.1016/j.ejmech.2009.12.036

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