2x2l

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(New page: '''Unreleased structure''' The entry 2x2l is ON HOLD Authors: Knowles, P.P., Murray-Rust, J., Kjaer, S., McDonald, N.Q. Description: Crystal Structure of phosphorylated RET tyrosine ki...)
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'''Unreleased structure'''
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[[Image:2x2l.jpg|left|200px]]
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The entry 2x2l is ON HOLD
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{{STRUCTURE_2x2l| PDB=2x2l | SCENE= }}
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Authors: Knowles, P.P., Murray-Rust, J., Kjaer, S., McDonald, N.Q.
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===CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN WITH INHIBITOR===
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Description: Crystal Structure of phosphorylated RET tyrosine kinase domain with inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:10:20 2010''
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{{ABSTRACT_PUBMED_20117004}}
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==About this Structure==
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2X2L is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X2L OCA].
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==Reference==
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<ref group="xtra">PMID:20117004</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Kjaer, S.]]
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[[Category: Knowles, P P.]]
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[[Category: Mcdonald, N Q.]]
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[[Category: Murray-Rust, J.]]
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[[Category: Disease mutation]]
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[[Category: Gdnf receptor]]
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[[Category: Hirschsprung disease]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphotransferase]]
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[[Category: Proto-oncogene]]
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[[Category: Ret]]
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[[Category: Transferase]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 17:16:03 2010''

Revision as of 15:16, 10 February 2010

Image:2x2l.jpg

Template:STRUCTURE 2x2l

CRYSTAL STRUCTURE OF PHOSPHORYLATED RET TYROSINE KINASE DOMAIN WITH INHIBITOR

Template:ABSTRACT PUBMED 20117004

About this Structure

2X2L is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Mologni L, Rostagno R, Brussolo S, Knowles PP, Kjaer S, Murray-Rust J, Rosso E, Zambon A, Scapozza L, McDonald NQ, Lucchini V, Gambacorti-Passerini C. Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1482-96. Epub 2010 Jan 11. PMID:20117004 doi:10.1016/j.bmc.2010.01.011

Page seeded by OCA on Wed Feb 10 17:16:03 2010

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