3k98

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3k98.jpg|left|200px]]
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The entry 3k98 is ON HOLD until Paper Publication
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{{STRUCTURE_3k98| PDB=3k98 | SCENE= }}
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Authors: Gajiwala, K.S., Davies II, J.F.
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===HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide===
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Description: HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:51:59 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19908836 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19908836}}
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==About this Structure==
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3K98 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K98 OCA].
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==Reference==
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<ref group="xtra">PMID:19908836</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Gajiwala, K S.]]
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[[Category: II, J F.Davies.]]
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[[Category: Acetylation]]
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[[Category: Alternative splicing]]
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[[Category: Atp binding domain]]
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[[Category: Atp-binding]]
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[[Category: Chaperone]]
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[[Category: Cytoplasm]]
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[[Category: Hsp90]]
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[[Category: Inhibition]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Stress response]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 17:23:58 2010''

Revision as of 15:23, 10 February 2010

Template:STRUCTURE 3k98

HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide

Template:ABSTRACT PUBMED 19908836

About this Structure

3K98 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kung PP, Huang B, Zhang G, Zhou JZ, Wang J, Digits JA, Skaptason J, Yamazaki S, Neul D, Zientek M, Elleraas J, Mehta P, Yin MJ, Hickey MJ, Gajiwala KS, Rodgers C, Davies JF, Gehring MR. Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. J Med Chem. 2010 Jan 14;53(1):499-503. PMID:19908836 doi:10.1021/jm901209q

Page seeded by OCA on Wed Feb 10 17:23:58 2010

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