3l58

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3l58.jpg|left|200px]]
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The entry 3l58 is ON HOLD
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{{STRUCTURE_3l58| PDB=3l58 | SCENE= }}
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Authors: Strickland, C., Zhu, Z.
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===Structure of BACE Bound to SCH589432===
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Description: Structure of BACE Bound to SCH589432
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:15:49 2010''
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{{ABSTRACT_PUBMED_20043696}}
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==About this Structure==
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3L58 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L58 OCA].
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==Reference==
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<ref group="xtra">PMID:20043696</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Strickland, C.]]
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[[Category: Zhu, Z.]]
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[[Category: Alternative splicing]]
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[[Category: Alzheimer]]
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[[Category: Aspartyl protease]]
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[[Category: Bace1]]
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[[Category: Disulfide bond]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Endosome]]
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[[Category: Glycoprotein]]
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[[Category: Golgi apparatus]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:28:24 2010''

Revision as of 08:28, 17 February 2010

Template:STRUCTURE 3l58

Structure of BACE Bound to SCH589432

Template:ABSTRACT PUBMED 20043696

About this Structure

3L58 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC. Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation ( parallel) (1). J Med Chem. 2010 Feb 11;53(3):951-65. PMID:20043696 doi:10.1021/jm901408p

Page seeded by OCA on Wed Feb 17 10:28:24 2010

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