3l13
From Proteopedia
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+ | [[Image:3l13.jpg|left|200px]] | ||
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3l13", creates the "Structure Box" on the page. | ||
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+ | {{STRUCTURE_3l13| PDB=3l13 | SCENE= }} | ||
- | + | ===Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors=== | |
- | Description: Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 | + | <!-- |
+ | The line below this paragraph, {{ABSTRACT_PUBMED_20050669}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 20050669 is the PubMed ID number. | ||
+ | --> | ||
+ | {{ABSTRACT_PUBMED_20050669}} | ||
+ | |||
+ | ==About this Structure== | ||
+ | 3L13 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L13 OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:20050669</ref><references group="xtra"/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
+ | [[Category: Murray, J M.]] | ||
+ | [[Category: Wiesmann, C.]] | ||
+ | [[Category: Atp-binding]] | ||
+ | [[Category: Kinase]] | ||
+ | [[Category: Nucleotide-binding]] | ||
+ | [[Category: Pi3k-gamma p110 gamma]] | ||
+ | [[Category: Transferase]] | ||
+ | |||
+ | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:29:34 2010'' |
Revision as of 08:29, 17 February 2010
Crystal Structures of Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors
Template:ABSTRACT PUBMED 20050669
About this Structure
3L13 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sutherlin DP, Sampath D, Berry M, Castanedo G, Chang Z, Chuckowree I, Dotson J, Folkes A, Friedman L, Goldsmith R, Heffron T, Lee L, Lesnick J, Lewis C, Mathieu S, Nonomiya J, Olivero A, Pang J, Prior WW, Salphati L, Sideris S, Tian Q, Tsui V, Wan NC, Wang S, Wiesmann C, Wong S, Zhu BY. Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer. J Med Chem. 2010 Feb 11;53(3):1086-97. PMID:20050669 doi:10.1021/jm901284w
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