3ksy

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ksy.jpg|left|200px]]
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The entry 3ksy is ON HOLD until Paper Publication
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{{STRUCTURE_3ksy| PDB=3ksy | SCENE= }}
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Authors: Gureasko, J., Kuchment, O., Kuriyan, J.
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===Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)===
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Description: Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 16:56:46 2010''
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{{ABSTRACT_PUBMED_20133692}}
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==Disease==
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Known disease associated with this structure: Fibromatosis, gingival OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan syndrome 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]], Noonan-like/multiple giant cell lesion syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=182530 182530]]
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==About this Structure==
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3KSY is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSY OCA].
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==Reference==
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<ref group="xtra">PMID:20133692</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Gureasko, J.]]
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[[Category: Kuchment, O.]]
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[[Category: Kuriyan, J.]]
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[[Category: Disease mutation]]
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[[Category: Guanine-nucleotide releasing factor]]
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[[Category: Ra]]
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[[Category: Ras activator]]
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[[Category: Signaling protein]]
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[[Category: Son of sevenless]]
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[[Category: So]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:36:29 2010''

Revision as of 08:36, 17 February 2010

Template:STRUCTURE 3ksy

Contents

Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)

Template:ABSTRACT PUBMED 20133692

Disease

Known disease associated with this structure: Fibromatosis, gingival OMIM:[182530], Noonan syndrome 4 OMIM:[182530], Noonan-like/multiple giant cell lesion syndrome OMIM:[182530]

About this Structure

3KSY is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gureasko J, Kuchment O, Makino DL, Sondermann H, Bar-Sagi D, Kuriyan J. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc Natl Acad Sci U S A. 2010 Feb 4. PMID:20133692

Page seeded by OCA on Wed Feb 17 10:36:29 2010

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