2cn2
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2CN2 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ | + | 2CN2 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Xyloglucan-specific_endo-beta-1,4-glucanase Xyloglucan-specific endo-beta-1,4-glucanase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.151 3.2.1.151]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CN2 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: Clostridium thermocellum]] | [[Category: Clostridium thermocellum]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Xyloglucan-specific endo-beta-1,4-glucanase]] | ||
[[Category: Baumann, M.J.]] | [[Category: Baumann, M.J.]] | ||
[[Category: Brumer, H.]] | [[Category: Brumer, H.]] | ||
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[[Category: xyloglucanase]] | [[Category: xyloglucanase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:09:01 2007'' |
Revision as of 08:04, 30 October 2007
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CRYSTAL STRUCTURES OF CLOSTRIDIUM THERMOCELLUM XYLOGLUCANASE
Overview
The enzymatic degradation of the plant cell wall is central both to the, natural carbon cycle and, increasingly, to environmentally friendly routes, to biomass conversion, including the production of biofuels. The plant, cell wall is a complex composite of cellulose microfibrils embedded in, diverse polysaccharides collectively termed hemicelluloses. Xyloglucan is, one such polysaccharide whose hydrolysis is catalyzed by diverse, xyloglucanases. Here we present the structure of the Clostridium, thermocellum xyloglucanase Xgh74A in both apo and ligand-complexed forms., The structures, in combination with mutagenesis data on the catalytic, residues and the kinetics and specificity of xyloglucan hydrolysis reveal, a complex subsite specificity accommodating seventeen monosaccharide, moieties ... [(full description)]
About this Structure
2CN2 is a [Single protein] structure of sequence from [Clostridium thermocellum] with CD as [ligand]. Active as [Xyloglucan-specific endo-beta-1,4-glucanase], with EC number [3.2.1.151]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structures of Clostridium thermocellum xyloglucanase, XGH74A, reveal the structural basis for xyloglucan recognition and degradation., Martinez-Fleites C, Guerreiro CI, Baumann MJ, Taylor EJ, Prates JA, Ferreira LM, Fontes CM, Brumer H, Davies GJ, J Biol Chem. 2006 Aug 25;281(34):24922-33. Epub 2006 Jun 13. PMID:16772298
Page seeded by OCA on Tue Oct 30 10:09:01 2007
Categories: Clostridium thermocellum | Single protein | Xyloglucan-specific endo-beta-1,4-glucanase | Baumann, M.J. | Brumer, H. | Davies, G.J. | Ferreira, L.M.A. | Fontes, C.M.G.A. | Guerreiro, C.I. | Martinez-Fleites, C. | Prates, J.A.M. | Taylor, E.J. | CD | Gh74 family | Glycosylhydrolase | Hydrolase | Xyloglucanase
