3kqc
From Proteopedia
(Difference between revisions)
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| + | [[Image:3kqc.jpg|left|200px]] | ||
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| + | {{STRUCTURE_3kqc| PDB=3kqc | SCENE= }} | ||
| - | + | ===Factor xa in complex with the inhibitor 6-(2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6- dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one=== | |
| - | Description: Factor xa in complex with the inhibitor 6-(2'-(methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6-dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20100660}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20100660 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20100660}} | ||
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| + | ==About this Structure== | ||
| + | 3KQC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KQC OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20100660</ref><references group="xtra"/> | ||
| + | [[Category: Coagulation factor Xa]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Sheriff, S.]] | ||
| + | [[Category: Blood coagulation]] | ||
| + | [[Category: Blood coagulation factor]] | ||
| + | [[Category: Calcium]] | ||
| + | [[Category: Calcium- binding]] | ||
| + | [[Category: Egf-like domain]] | ||
| + | [[Category: Gamma-carboxyglutamic acid]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Plasma]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Protein inhibitor complex]] | ||
| + | [[Category: Secreted]] | ||
| + | [[Category: Serine protease]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:36:09 2010'' | ||
Revision as of 11:36, 25 February 2010
Factor xa in complex with the inhibitor 6-(2'- (methylsulfonyl)biphenyl-4-yl)-1-(3-(5-oxo-4,5-dihydro-1h- 1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-5,6- dihydro-1h-pyrazolo[3,4-c]pyridin-7(4h)-one
Template:ABSTRACT PUBMED 20100660
About this Structure
3KQC is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Quan ML, Pinto DJ, Rossi KA, Sheriff S, Alexander RS, Amparo E, Kish K, Knabb RM, Luettgen JM, Morin P, Smallwood A, Woerner FJ, Wexler RR. Phenyltriazolinones as potent factor Xa inhibitors. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1373-7. Epub 2010 Jan 11. PMID:20100660 doi:10.1016/j.bmcl.2010.01.011
Page seeded by OCA on Thu Feb 25 13:36:09 2010
