User:Tilman Schirmer/Sandbox 99
From Proteopedia
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| - | The peptide bond formation is a condensation reaction between the carboxyl group of the amino acid n<sub>i</sub> and the amino group of the amino acid n<sub>i+1</sub>. | + | The peptide bond formation is a condensation reaction between the carboxyl group of the amino acid n<sub>i</sub> and the amino group of the amino acid n<sub>i+1</sub>. |
| - | The <scene name='User:Tilman_Schirmer/Sandbox_99/Phi_angle/2'>Phi torsion angle</scene> is defined by the four atoms φ = C - N - C<sub>α</sub> - C (yellow: bond between N - C<sub>α</sub>). | + | The <scene name='User:Tilman_Schirmer/Sandbox_99/Phi_angle/2'>Phi torsion angle</scene> is defined by the four atoms φ = C - N - C<sub>α</sub> - C (yellow: bond between N - C<sub>α</sub>). |
The <scene name='User:Tilman_Schirmer/Sandbox_99/Psi_angle/2'>Psi torsion angle</scene> is defined by the four atoms ψ = N - C<sub>α</sub> - C - N (green: bond between C<sub>α</sub> - C). | The <scene name='User:Tilman_Schirmer/Sandbox_99/Psi_angle/2'>Psi torsion angle</scene> is defined by the four atoms ψ = N - C<sub>α</sub> - C - N (green: bond between C<sub>α</sub> - C). | ||
The <scene name='User:Tilman_Schirmer/Sandbox_99/Omega_angle/7'>Omega torsion angle</scene> is defined by the four atoms ω = C<sub>α</sub> - C - N - C<sub>α</sub> (orange: bond between C - N). | The <scene name='User:Tilman_Schirmer/Sandbox_99/Omega_angle/7'>Omega torsion angle</scene> is defined by the four atoms ω = C<sub>α</sub> - C - N - C<sub>α</sub> (orange: bond between C - N). | ||
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| + | The peptide bond is a resonance structure between two limiting states. Therefore the N-C bond has a partial double bond character and the atoms/groups C<sub>α</sub>, HN, C, C=O are within one plane. Peptide bonds are usually in trans conformation (ω torsion angle= 180°) due to sterical hindrance between C<sub>β</sub> and the C=O carbonyl. Cis conformation can occur only for the peptide bonds preceding Pro or Gly residue, where no C<sub>β</sub> is interfering. | ||
Revision as of 16:39, 25 February 2010
Peptide bond
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The peptide bond formation is a condensation reaction between the carboxyl group of the amino acid ni and the amino group of the amino acid ni+1.
The is defined by the four atoms φ = C - N - Cα - C (yellow: bond between N - Cα).
The is defined by the four atoms ψ = N - Cα - C - N (green: bond between Cα - C).
The is defined by the four atoms ω = Cα - C - N - Cα (orange: bond between C - N).
The peptide bond is a resonance structure between two limiting states. Therefore the N-C bond has a partial double bond character and the atoms/groups Cα, HN, C, C=O are within one plane. Peptide bonds are usually in trans conformation (ω torsion angle= 180°) due to sterical hindrance between Cβ and the C=O carbonyl. Cis conformation can occur only for the peptide bonds preceding Pro or Gly residue, where no Cβ is interfering.
