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Cory Tiedeman Sandbox 1
From Proteopedia
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[[Image:1one.png|left|200px]] | [[Image:1one.png|left|200px]] | ||
| + | Enolase is an enzyme that catalyzes a reaction of glycolysis. Glycolysis converts glucose into two 3-carbon molecules called pyrubate. The energy released during glycolysis is used to make ATP.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=486|}}</ref> Enolase is used to convert2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the 9th reaction of glycolysis.<ref>{{text book |author=Voet, Donald; Voet, Judith C.; Pratt, Charlotte W.|title=Fundamentals of Biochemistry: Life at the Molecular Level|edition= 3|pages=500|}}</ref> | ||
{{STRUCTURE_1one | PDB=1one | SCENE= }} | {{STRUCTURE_1one | PDB=1one | SCENE= }} | ||
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==Structure== | ==Structure== | ||
<scene name='Cory_Tiedeman_Sandbox_1/Secondary_structure/1'>Secondary Structure</scene> | <scene name='Cory_Tiedeman_Sandbox_1/Secondary_structure/1'>Secondary Structure</scene> | ||
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| + | ==Mechanism== | ||
| + | The | ||
| + | <scene name='Cory_Tiedeman_Sandbox_1/Active_sice/1'>active site</scene> of enolase as shown, involves Lys 345, Lys 396, Glu 168, Glu 211, and His 159. | ||
| + | <scene name='Cory_Tiedeman_Sandbox_1/Mg/1'>Mg 2+</scene> | ||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
Revision as of 03:31, 1 March 2010
Enolase is an enzyme that catalyzes a reaction of glycolysis. Glycolysis converts glucose into two 3-carbon molecules called pyrubate. The energy released during glycolysis is used to make ATP.[1] Enolase is used to convert2-phosphoglycerate (2PG) to phosphoenolpyruvate (PEP) in the 9th reaction of glycolysis.[2]
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| 1one, resolution 1.80Å () | |||||||||
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| Ligands: | , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Phosphopyruvate hydratase, with EC number 4.2.1.11 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Structure
Mechanism
The of enolase as shown, involves Lys 345, Lys 396, Glu 168, Glu 211, and His 159.
