2-Oxoglutarate Dehydrogenase
From Proteopedia
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- | == | + | ==2-Oxoglutarate Dehydrogenase E1o== |
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- | + | {{STRUCTURE_ 2jgd | PDB= 2jgd | SCENE= }} | |
- | + | 2-Oxoglutarate Dehydrogenase E1o is part of the 2-Oxoglutarate Dehydrogenase multi enzyme complex. E1o catalyzes the that catalyzes the the decarboxylation of R-C-OH complexed with thiamine diphosphate to R-C=O. This subunit is a homo-dimer and one of three enzymes that make up the multi-enzyme complex of 2-Oxoglutarate Dehydrogenase. each of the monomers that make up the homo-dimer has an <scene name='Lucas_Evans_Sandbox/Amp1/1'>Adenosine Monophosphate</scene> cofactor that facilitates the catalysis. This subunit is involved in the metabolic citric acid cycle. E1o is not categorized in the Structural Classification of Proteins (SCOP); hoevever, the <scene name='Lucas_Evans_Sandbox/Secondary_structure/1'>secondary structure</scene> of one of the dimers shows that this enzyme has large sections of alpha-helices followed by a small section of parallel beta-pleated sheets. | |
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- | {{STRUCTURE_ 2jgd | PDB= 2jgd | SCENE= }} | + |
Revision as of 22:01, 1 March 2010
2-Oxoglutarate Dehydrogenase E1o
Template:STRUCTURE 2jgd 2-Oxoglutarate Dehydrogenase E1o is part of the 2-Oxoglutarate Dehydrogenase multi enzyme complex. E1o catalyzes the that catalyzes the the decarboxylation of R-C-OH complexed with thiamine diphosphate to R-C=O. This subunit is a homo-dimer and one of three enzymes that make up the multi-enzyme complex of 2-Oxoglutarate Dehydrogenase. each of the monomers that make up the homo-dimer has an cofactor that facilitates the catalysis. This subunit is involved in the metabolic citric acid cycle. E1o is not categorized in the Structural Classification of Proteins (SCOP); hoevever, the of one of the dimers shows that this enzyme has large sections of alpha-helices followed by a small section of parallel beta-pleated sheets.
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, David Canner, Lucas Evans, Alexander Berchansky, Joel L. Sussman