2asi
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2ASI is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]] with NAG as [[http://en.wikipedia.org/wiki/ligand ligand]]. This structure superseeds the now removed PDB entry 1ASI. Active as [[http://en.wikipedia.org/wiki/ | + | 2ASI is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Rhizomucor_miehei Rhizomucor miehei]] with NAG as [[http://en.wikipedia.org/wiki/ligand ligand]]. This structure superseeds the now removed PDB entry 1ASI. Active as [[http://en.wikipedia.org/wiki/Mucorpepsin Mucorpepsin]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.23 3.4.23.23]]. Structure known Active Site: ACT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2ASI OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution., Yang J, Teplyakov A, Quail JW, J Mol Biol. 1997 May 2;268(2):449-59. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9159482 9159482] | Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution., Yang J, Teplyakov A, Quail JW, J Mol Biol. 1997 May 2;268(2):449-59. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9159482 9159482] | ||
| + | [[Category: Mucorpepsin]] | ||
[[Category: Rhizomucor miehei]] | [[Category: Rhizomucor miehei]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: zymogen]] | [[Category: zymogen]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 10:09:44 2007'' |
Revision as of 08:05, 30 October 2007
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ASPARTIC PROTEINASE
Overview
The crystal structure of the aspartic proteinase from Rhizomucor miehei, (RMP, EC 3. 4. 23. 23) has been refined to 2.15 A resolution to a, crystallographic R-value of 0.215 and an Rfree of 0.281. The, root-mean-square (r.m.s.) error for the atomic coordinates estimated from, a Luzzati plot is 0.2 A. The r.m.s. deviations for the bond distances and, bond angles from ideality are 0.01 A and 1.7 degrees, respectively. RMP, contains two domains that consist predominantly of beta-sheets. A large, substrate-binding cleft is clearly visible between the two domains, and, the two catalytic residues Asp38 and Asp237 are located in the middle of, the cleft with a water molecule bridging the carboxyl groups of Asp38 and, Asp237. Due to crystal packing, the C-terminal domain is more mobile than, the ... [(full description)]
About this Structure
2ASI is a [Single protein] structure of sequence from [Rhizomucor miehei] with NAG as [ligand]. This structure superseeds the now removed PDB entry 1ASI. Active as [Mucorpepsin], with EC number [3.4.23.23]. Structure known Active Site: ACT. Full crystallographic information is available from [OCA].
Reference
Crystal structure of the aspartic proteinase from Rhizomucor miehei at 2.15 A resolution., Yang J, Teplyakov A, Quail JW, J Mol Biol. 1997 May 2;268(2):449-59. PMID:9159482
Page seeded by OCA on Tue Oct 30 10:09:44 2007
