2i4q
From Proteopedia
(Difference between revisions)
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===Human renin/PF02342674 complex=== | ===Human renin/PF02342674 complex=== | ||
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| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_17574423}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 17574423 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_17574423}} | ||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2I4Q is a 2 chains structure | + | 2I4Q is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4Q OCA]. |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:17574423</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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[[Category: Mochalkin, I.]] | [[Category: Mochalkin, I.]] | ||
[[Category: Zhang, E.]] | [[Category: Zhang, E.]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
[[Category: Renin inhibitor]] | [[Category: Renin inhibitor]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 14:37:40 2010'' |
Revision as of 12:37, 3 March 2010
Contents |
Human renin/PF02342674 complex
Template:ABSTRACT PUBMED 17574423
Disease
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]
About this Structure
2I4Q is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Powell NA, Ciske FL, Cai C, Holsworth DD, Mennen K, Van Huis CA, Jalaie M, Day J, Mastronardi M, McConnell P, Mochalkin I, Zhang E, Ryan MJ, Bryant J, Collard W, Ferreira S, Gu C, Collins R, Edmunds JJ. Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors. Bioorg Med Chem. 2007 Sep 1;15(17):5912-49. Epub 2007 Jun 2. PMID:17574423 doi:10.1016/j.bmc.2007.05.069
Page seeded by OCA on Wed Mar 3 14:37:40 2010
