2x23

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2x23.jpg|left|200px]]
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The entry 2x23 is ON HOLD until Paper Publication
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{{STRUCTURE_2x23| PDB=2x23 | SCENE= }}
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Authors: Luckner, S.R., Liu, N., am Ende, C.W., Tonge, P.J., Kisker, C.
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===CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70===
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Description: crystal structure of M. tuberculosis InhA inhibited by PT70
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:12:53 2010''
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{{ABSTRACT_PUBMED_14623976}}
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==About this Structure==
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2X23 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X23 OCA].
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==Reference==
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<ref group="xtra">PMID:14623976</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Ende, C W.Am.]]
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[[Category: Kisker, C.]]
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[[Category: Liu, N.]]
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[[Category: Luckner, S R.]]
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[[Category: Tonge, P J.]]
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[[Category: Antibiotic resistance]]
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[[Category: Fatty acid biosynthesis]]
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[[Category: Lipid synthesis]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:29:34 2010''

Revision as of 14:29, 3 March 2010

Image:2x23.jpg

Template:STRUCTURE 2x23

CRYSTAL STRUCTURE OF M. TUBERCULOSIS INHA INHIBITED BY PT70

Template:ABSTRACT PUBMED 14623976

About this Structure

2X23 is a 4 chains structure with sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Rawat R, Whitty A, Tonge PJ. The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13881-6. Epub 2003 Nov 17. PMID:14623976 doi:10.1073/pnas.2235848100

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