High school teachers' resources

From Proteopedia

Revision as of 19:30, 5 March 2010

Physical model designed by a SMART Team.

Below are listed resources for high school (secondary school) teachers that concern 3D macromolecular structure, both within Proteopedia and outside it. High school teachers typically teach students of ages about 14-18. Some of the resources listed here are also appropriate for younger students (K-12), or older students including adults.

Macromolecules for High School Curricula

These molecules fit nicely into most secondary school biology curricula.

Molecule	At BioMolecular Explorer 3D	At Molecule of the Month	At Proteopedia	See Also
Antibody	Antibody: Immune System	Antibodies
Collagen	Collagen: Connective Tissue	Collagen		Collagen Structure Assembly Movies
DNA	DNA: Genetic Inheritance	DNA	DNA	Exploring DNA DNA Resources
Hemoglobin	Hemoglobin: Respiration	Hemoglobin	Hemoglobin
HIV Protease	HIV Protease: Infectious Diseases - AIDS Virus	HIV-1 Protease	HIV-1 Protease
Lactase	Lactase: Digestion	(cf. Pepsin, Trypsin)
Lipid Bilayers	Lipid Bilayers and Channels: Cell Structure		Gramicidin Channel in Lipid Bilayer
Myosin	Myosin: A Molecular Motor	Myosin
Nucleosomes	Nucleosomes: Chromosome Structure	Nucleosome	Nucleosome

Within Proteopedia

A SMART Team in action.

• About Macromolecular Structure lists articles that explain and define many macromolecular structure concepts, including biological units, hydrogen bonds, ligands, peptide, Protein Data Bank and PDB identification codes, and resolution.
• Importance of 3D macromolecular structure:
  • Highest impact structures of all time.
  • Structures saving the most lives.
• Molecular Workbench, ready-to-use discovery-based learning activities, at the high school level, with built-in assessment.

Protein folding simulations in Molecular Workbench. Click image for details.

• SMART Teams consist of high school teachers and their students, collaborating with scientists to use rapid-prototyping technology to make 3D physical models of macromolecules. Recently, they are also making articles in Proteopedia, for example:
  • A Physical Model of the β2-Adrenergic Receptor, from the Madison West High School 2008 SMART Team.
• Teaching Scenes, Tutorials, and Educators' Pages, including
  • Lac repressor with morphs of DNA being bent.
  • Avian Influenza Neuraminidase, Tamiflu and Relenza
• Teaching Strategies Using Proteopedia
• Quizzes within Proteopedia

Outside Proteopedia

• Biomodel, 3D molecular visualization resources on many topics, also en español and other languages.
• BioMolecular Explorer 3D (bme3d.molviz.org). In addition to the molecules listed above, BME3D includes sections on carbohydrates, protein, lipids, vitamins, and water.

Earring representing the DNA double helix. Instructions available from Genetic Jewels.

• K-12 Resources at molvisindex.org, the World Index of Molecular Visualization Resources. Includes how to make DNA earrings, and balloon molecules.
• Molecule of the Month. Illustrated introductory articles on over one hundred macromolecules. Interactive 3D visualization is available in the most recent articles.
• MolviZ.Org includes the Top Five Molecular Visualization Resources, an illustrated Atlas of Macromolecules, a tutorial on collagen, a tool for exploring any macromolecule (FirstGlance in Jmol), tools for visualizing evolutionarily conserved patches on the surfaces of protein molecules, Toobers, physical molecular models, and more.