3kvm

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Revision as of 13:22, 10 March 2010

Template:STRUCTURE 3kvm

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with amino-benzoic acid inhibitor 951 at 2.00A resolution

Template:ABSTRACT PUBMED 20153645

About this Structure

3KVM is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • McLean LR, Zhang Y, Degnen W, Peppard J, Cabel D, Zou C, Tsay JT, Subramaniam A, Vaz RJ, Li Y. Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1981-4. Epub 2010 Jan 25. PMID:20153645 doi:10.1016/j.bmcl.2010.01.115

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