2b5t

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===2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules===
===2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules===
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{{ABSTRACT_PUBMED_16973611}}
==Disease==
==Disease==
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==About this Structure==
==About this Structure==
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2B5T is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5T OCA].
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2B5T is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5T OCA].
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==Reference==
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<ref group="xtra">PMID:16973611</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Carrell, R W.]]
[[Category: Carrell, R W.]]
[[Category: Huntington, J A.]]
[[Category: Huntington, J A.]]
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[[Category: Johnson, D J.D.]]
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[[Category: Johnson, D J.]]
[[Category: Li, W.]]
[[Category: Li, W.]]
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[[Category: Luis, S.]]
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[[Category: Luis, S A.]]
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[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:14:57 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:03:40 2010''

Revision as of 07:03, 17 March 2010

Template:STRUCTURE 2b5t

Contents

2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules

Template:ABSTRACT PUBMED 16973611

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2B5T is a 5 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Johnson DJ, Langdown J, Li W, Luis SA, Baglin TP, Huntington JA. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J Biol Chem. 2006 Nov 17;281(46):35478-86. Epub 2006 Sep 13. PMID:16973611 doi:10.1074/jbc.M607204200

Page seeded by OCA on Wed Mar 17 09:03:40 2010

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