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2we4
From Proteopedia
(Difference between revisions)
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| + | {{STRUCTURE_2we4| PDB=2we4 | SCENE= }} | ||
| - | + | ===CARBAMATE KINASE FROM ENTEROCOCCUS FAECALIS BOUND TO A SULFATE ION AND TWO WATER MOLECULES, WHICH MIMIC THE SUBSTRATE CARBAMYL PHOSPHATE=== | |
| - | Description: Carbamate kinase from Enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20188742}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20188742 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20188742}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | 2WE4 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WE4 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20188742</ref><ref group="xtra">PMID:10211841</ref><ref group="xtra">PMID:10860751</ref><references group="xtra"/> | ||
| + | [[Category: Carbamate kinase]] | ||
| + | [[Category: Enterococcus faecalis]] | ||
| + | [[Category: Gil-Ortiz, F.]] | ||
| + | [[Category: Marina, A.]] | ||
| + | [[Category: Ramon-Maiques, S.]] | ||
| + | [[Category: Rubio, V.]] | ||
| + | [[Category: Arginine catabolism]] | ||
| + | [[Category: Arginine metabolism]] | ||
| + | [[Category: Atp synthesy]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Open alpha/beta sheet]] | ||
| + | [[Category: Phosphotransferase]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:32:56 2010'' | ||
Revision as of 07:32, 17 March 2010
CARBAMATE KINASE FROM ENTEROCOCCUS FAECALIS BOUND TO A SULFATE ION AND TWO WATER MOLECULES, WHICH MIMIC THE SUBSTRATE CARBAMYL PHOSPHATE
Template:ABSTRACT PUBMED 20188742
About this Structure
2WE4 is a 4 chains structure with sequences from Enterococcus faecalis. Full crystallographic information is available from OCA.
Reference
- Ramon-Maiques S, Marina A, Guinot A, Gil-Ortiz F, Uriarte M, Fita I, Rubio V. Substrate binding and catalysis in carbamate kinase ascertained by crystallographic and site-directed mutagenesis studies: movements and significance of a unique globular subdomain of this key enzyme for fermentative ATP production in bacteria. J Mol Biol. 2010 Apr 16;397(5):1261-75. Epub 2010 Feb 25. PMID:20188742 doi:10.1016/j.jmb.2010.02.038
- Marina A, Alzari PM, Bravo J, Uriarte M, Barcelona B, Fita I, Rubio V. Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine. Protein Sci. 1999 Apr;8(4):934-40. PMID:10211841
- Ramon-Maiques S, Marina A, Uriarte M, Fita I, Rubio V. The 1.5 A resolution crystal structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic Archaeon pyrococcus furiosus, bound to ADP, confirms that this thermostable enzyme is a carbamate kinase, and provides insight into substrate binding and stability in carbamate kinases. J Mol Biol. 2000 Jun 2;299(2):463-76. PMID:10860751 doi:http://dx.doi.org/10.1006/jmbi.2000.3779
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