Interleukin-10
From Proteopedia
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== '''Interlukin-10''' '''[[2H24]]''' == | == '''Interlukin-10''' '''[[2H24]]''' == | ||
===Crystal structure of human IL-10=== | ===Crystal structure of human IL-10=== | ||
| - | This is a cytokine.<ref> | + | This is a cytokine.<ref>PMID:16982608</ref> Cytokines function as....<ref>Reference 2</ref> |
| - | + | Interleukin-10 is a very powerful anti-inflammatory cytokine. It is also a cytokine synthesis inhibitory factor. These are the reasons that IL-10 is investigated for its role in patients with Rheumatoid Arthritis (RA) as well as those with osteoarthritis (OA).(Katsikis et al.) | |
| + | RA is an autoimmune disorder that affects the synovial tissues of the affected persons, via chronic synovitis. The chronic synovitis often results in joint destruction due to re-absorption of bone and (Katsikis et al and Nemec et al) | ||
| + | IL-10 is found to spontaneously be produce in synovial tissue of patients with RA and OA but not in normal synovial tissue. | ||
| + | The variation in secretion of IL-10 is thought to be at about 75% under the control of the genetics of the individual. (Nemec) | ||
| + | Make a link to the wiki website that talks about cytokines. | ||
| + | Make a link to RA | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_16982608}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16982608 is the PubMed ID number. | ||
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| - | {{ABSTRACT_PUBMED_16982608}} | ||
<table style="background-color:#ffffc0" cellpadding="8" width="95%" border="0"><tr><td>Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. [[User:Andrea Gorrell|Andrea Gorrell]].</td></tr> | <table style="background-color:#ffffc0" cellpadding="8" width="95%" border="0"><tr><td>Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. [[User:Andrea Gorrell|Andrea Gorrell]].</td></tr> | ||
Shelly Huebert | Shelly Huebert | ||
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<scene name='Sandbox_165/2h24_backbone/1'>ball and stick of 2h24</scene> | <scene name='Sandbox_165/2h24_backbone/1'>ball and stick of 2h24</scene> | ||
Revision as of 01:09, 18 March 2010
Contents |
Interlukin-10 2H24
Crystal structure of human IL-10
This is a cytokine.[1] Cytokines function as....[2] Interleukin-10 is a very powerful anti-inflammatory cytokine. It is also a cytokine synthesis inhibitory factor. These are the reasons that IL-10 is investigated for its role in patients with Rheumatoid Arthritis (RA) as well as those with osteoarthritis (OA).(Katsikis et al.) RA is an autoimmune disorder that affects the synovial tissues of the affected persons, via chronic synovitis. The chronic synovitis often results in joint destruction due to re-absorption of bone and (Katsikis et al and Nemec et al)
IL-10 is found to spontaneously be produce in synovial tissue of patients with RA and OA but not in normal synovial tissue.
The variation in secretion of IL-10 is thought to be at about 75% under the control of the genetics of the individual. (Nemec) Make a link to the wiki website that talks about cytokines. Make a link to RA
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| Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell. |
Proteopedia Page Contributors and Editors (what is this?)
Shelly Huebert, Andrea Gorrell, Alexander Berchansky, David Canner, Jaime Prilusky, Michal Harel
